The dynamic consequences of amygdala damage on threat processing in Urbach-Wiethe Disease. A commentary on Pishnamazi et al. (2016).

نویسندگان

  • Ruud Hortensius
  • David Terburg
  • Barak Morgan
  • Dan J Stein
  • Jack van Honk
  • Beatrice de Gelder
چکیده

Ruud Hortensius , David Terburg , Barak Morgan , Dan J. Stein , Jack van Honk b,c,g and Beatrice de Gelder a,b,* a Brain and Emotion Laboratory, Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands b Department of Psychiatry and Mental Health, University of Cape Town, J-Block, Groote Schuur Hospital, Cape Town, South Africa c Experimental Psychology, Utrecht University, Utrecht, The Netherlands d Global Risk Governance Program, Department of Public Law and Institute for Humanities in Africa, University of Cape Town, Cape Town, South Africa e DST-NRF Centre of Excellence in Human Development, DVC Research Office, University of Witwatersrand, Johannesburg, South Africa f Department of Psychiatry and Medical Research Council (MRC) Unit on Anxiety & Stress Disorders, University of Cape Town, J-Block, Groote Schuur Hospital, Cape Town, South Africa g Institute of Infectious Diseases and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa

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Attentional bias towards and away from fearful faces is modulated by developmental amygdala damage

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Amygdala, affect and cognition: evidence from 10 patients with Urbach-Wiethe disease.

Patients with Urbach-Wiethe disease constitute a unique nature experiment as more than half have bilaterally symmetrical damage in the amygdaloid region. Ten such patients were studied neuropsychologically and, nine of them, neuroradiologically with static (CT) and functional imaging techniques [single-photon emission computed tomography (SPECT) and PET]. Their principal bilateral amygdala dama...

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Amygdala control of emotion-induced forgetting and remembering: evidence from Urbach-Wiethe disease.

When presented in a neutral context, emotional items interfere with episodic encoding of temporally contiguous non-emotional items, resulting in dissociable valence-dependent retrograde and arousal-dependent anterograde modulatory effects. By studying two rare patients with congenital lipoid proteinosis (Urbach-Wiethe) and a focal disease emphasis on the basolateral amygdala (BLA), we demonstra...

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عنوان ژورنال:
  • Cortex; a journal devoted to the study of the nervous system and behavior

دوره 88  شماره 

صفحات  -

تاریخ انتشار 2017